Prevalence of comorbidities in deceased patients with COVID-19: A systematic review.

BACKGROUND: In December 2019, a new disease, coronavirus disease (COVID-19), emerged, which put several countries on a state of alert. Because it is a novel virus, several aspects and factors that contribute to the evolution of pathogenesis are still unknown and need to be better understood. Therefore, a systematic review is necessary to investigate the association between COVID-19 infection and chronic nontransmissible disease in patients who have died of COVID-19. METHODS: This was a systematic review of the literature for observational studies published between December 2019 and September 2020. The protocol for this systematic review was registered in the International prospective register of systematic reviews (PROSPERO) under the number CRD42020176249. RESULTS: In the 31 studies analyzed, a total of 421,872 (100%) patients were infected with COVID-19, and, of these, 45,399 (10.8%) died. The 3 most prevalent comorbidities were hypertension, diabetes mellitus, and respiratory diseases, respectively. The cure/recovery rate was 89.2% (376,473). CONCLUSION: This review revealed a high percentage of comorbidities in the patients with COVID-19, especially those who died.

Epidemiological behavior of the COVID-19 contamination curve in Brazil: Time-series analysis.

Brazil is experiencing the greatest episode of sanitary collapse ever known in the country's history. Therefore, the relevance of this study is highlighted for the scientific advance of the epidemiological behavior of the virus in Brazil, enabling the development of analyses and discussions on the factors that influenced the high rates of contamination by SARS-CoV-2 in the country. Given the above, this study aims to analyze the epidemiological behavior of the COVID-19 contamination curve by epidemiological weeks (EW), in the years 2020-2021, in Brazil. This is an ecological study of time series, prepared using information collected through secondary means. The country of origin of the study is Brazil, and its main theme is the number of people infected during the COVID-19 pandemic, this being the dependent variable of the study. The data has been analyzed from February 23, 2020, when the first case was confirmed in Brazil, to January 1, 2022. In 2021, the country's graph shows an exponential growth, reaching a peak of approximately 250 new cases per 100,000 inhabitants in the 12th EW. This data represents the highest rate of the pandemic in Brazil, and did not vary significantly for the next twelve weeks. Thus, it was identified that Brazil was severely impacted by the new coronavirus, considering the high rates of confirmed cases of the virus in the country, the low adherence of the population to preventive measures, the late start of mass vaccination in the Brazilian population, and the lack of structure in the health system, which was not appropriately prepared for the high demand generated by COVID-19.